Lantus is an insulin glargine injection. Insulin glargine is recombinant human long acting insulin and it helps to lower the blood glucose. Lantus is the most useful medical solution for diabetic people. It is usually taken in combination with oral diabetes medications.
Lantus is created by recombinant DNA technology. It is consist of insulin glargine dissolved in a clear aqueous fluid. One milliliter of lantus contains 3.6378 mg (100IU) glargine insulin. The ingredients for 3 ml insulin cartridge are 30 mg zinc, 20 mg glycerol, 2.7 mg m-cresol and water for injection. Lantus has pH of approximately 4. Its pH can be adjusted by addition of aqueous solution of hydrochloric acid and sodium hydroxide.
You can take this insulin at any time during the day, but it should be taken at the same time every day. An extra dose of insulin may result in hypoglycemia; it is the most common adverse effect of insulin. So be careful while changing in insulin timing, insulin strength, and insulin type. Also monitor blood glucose regularly.
According to a new study on diabetes care, Lantus is more effective than NPH (Neutral Protamine Hagedorn). Treatment with Lantus resulted in predictable fasting blood glucose levels. Pediatric patients with type 1 diabetes and adult patients with type 2 diabetes should take lantus once in a day. Generally type 2 diabetes patients require long-acting insulin for the control of hyperglycemia.
Lantus is used for greater reduction in fasting blood glucose compared to NPH insulin patients. Generally lantus and NPH shows similar fasting plasma glucose variability. But more lantus patients feel injection site pain. Also there are some adverse events due to lantus treatment like skin reactions, lipodystrophy, hypoglycemia and allergic reactions. With the use of any insulin therapy sodium retention and edema may occur.
You cannot dilute or mix lantus with any other insulin. If lantus is mixed with any other solution, it may become cloudy. The time course of lantus action may vary in different individuals. The rate of absorption of insulin depends upon physical activity, blood supply and temperature. While taking lantus insulin you should learn proper injection technique and should monitor glucose level. Patients must be aware of special situations such as illness, emotional disturbances and stress. It may happen due to increased insulin dose, skipped meals and insufficient food intake. Patient should take extra care in pregnancy.
In lantus insulin treatment you should remember some points:
Without advice of your doctor do not change the insulin. Change in insulin manufacturer, type and strength depends upon your blood glucose level. You must check sugar levels before starting any insulin. Insulin injections are important for diabetes control, but along with an insulin dose exercise, diet and careful checking of your blood sugar levels are equally important.
Before starting any insulin treatment (lantus insulin included) you should inform your doctor about your all health problems. As the doctor can then study your health problems and adjust the insulin doses accordingly. Always follow your doctor’s instructions when on insulin treatment.