d chiro inositol in treatment of type 2 diabetes
D chiro inositol has been showing promising results in the treatment of people suffering from less severe form of diabetes; it has also helped women suffering from polycystic ovary syndrome. It is basically a white compound and is an important component of cell membranes. It performs several biological functions. Signaling molecules that direct cell behavior are assisted by d chiro inositol. This agent is known to reduce insulin resistance and thus help diabetic patients.
D chiro inositol is also found in plants and legumes. It is mainly found in the monomethylated or glycosylated forms in beans, buckwheat and other plants. Some microorganisms also have d chiro inositol. It has proven to effectively reduce blood sugar levels if eaten in the right quantity. Patients suffering from type 2 diabetes have low d chiro inositol in their muscles as compared to normal people. The only problem is that it is not available as yet in drug form or as a dietary supplement. It is well tolerated. If taken in large doses it causes diarrhea. However, till now no toxicity has been reported. Occasionally gastrointestinal problems like nausea are reported. Uterine contraction can also be seen in pregnant women when d chiro inositol is ingested.
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Sulfonylurea and d chiro inositol are used in combination as a new treatment. In studies conducted it was noted that the blood sugar levels came down to normal as a result of this combination. Insulin output was also seen to have increased. However, the disease does progress in spite of taking d chiro inositol and pancreatic insufficiency does occur. The results seen are comparable to the ones seen when sulfonylurea is taken in isolation. The only saving grace is that it does thwart the progression of the disease to a certain extent. Patients with a fasting blood glucose level of 180mg/dl or less can be treated with this combination. Even patients suffering from hyperglycemia can be treated.
It must be noted that this is still an untried means to increase insulin sensitivity. Cases of less acute diabetes can be treated along with women suffering from polycystic ovary syndrome. More research is however necessary to finally conclude its effectiveness.
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